Believe it or not, artichokes are one of the top vegetables in terms of antioxidant content. While you may not reap the benefits of artichokes by diving face first into a bowl of spinach artichoke dip, eating artichokes provides you with a lot of vitamin C, A, K, and more. Some artichoke extract supplements, which provide concentration of the vegetable’s protective compounds, include cynarin, chlorogenic acid, cymaroside, and luteolin. 

Due to the high fiber content and rich phytonutrient profile, artichokes are great for overall health. Some research shows that the compounds may help prevent serious conditions such as cancer and heart disease. They have also proven to positively impact digestive function. On top of all that, artichokes taste great, they are low in carbs, and are quite versatile. 

Because some compounds in artichokes have heart-promoting benefits, artichoke extract supplements have risen in popularity in recent years. These supplements are largely derived from the antioxidants and phytonutrients found in the leaves. Leaf extracts of the artichoke plant have liver-protectant properties, in addition to anti-carcinogenic, antioxidant, anti-viral, and antibacterial activity. 

Artichoke Nutrition

Available nutritional data indicates that a one-cup serving of cooked artichoke contains approximately:

• Calories: 90
• Fiber: 9.7 grams (g)
• Total carbohydrates: 20.2 g
• Total fat: 0.6 g
• Sugar: 1.7 g
• Protein: 4.9 g
• Sodium: 299 milligrams (mg)
• Riboflavin: 0.2 mg
• Folate: 151 micrograms (mcg)
• Magnesium: 71.4 mg
• Vitamin K: 25.2 mcg
• Potassium: 124 mg
• Zinc: 0.7 mg
• Calcium: 37.7 mg
• Niacin: 1.9 mg

Artichokes also contain some choline, vitamin A, selenium, beta-carotene, lutein, vitamin E, and zeaxanthin. Although artichokes provide many essential nutrients, they are particularly high in folate and vitamin K. Continue reading to learn more about their health benefits. 

They Protect Heart Health

Research shows that consuming artichokes and artichoke extract may help reduce unhealthy cholesterol levels and high blood pressure. People with high cholesterol have a higher risk of developing heart disease and experiencing stroke. Artichokes contain cynarin, a powerful substance that may help naturally bring cholesterol into a healthy range. Research indicates that the lipidic- and glycemic-reducing action of artichokes also helps protect against coronary heart disease. In a double-blind, randomized, controlled trial, researchers observed participants who supplemented with artichoke leaf extract. At the end of the study, participants experienced reductions in total cholesterol and triglyceride concentrations. 

They Are Rich In Fiber

Fiber is necessary for optimal digestive and heart function. Fiber can help relieve conditions like constipation and diarrhea, and it helps the body detox itself of extra  cholesterol, sugar, and toxins. A high-fiber diet has been associated with maintaining a healthy weight, in addition to reducing the risk of conditions like colon cancer and heart disease, among others. Fiber is the substance that pulls food through the intestines. Without fiber, you can suffer from digestive issues like constipation, energy spikes and dips, weight gain, bloating, mood swings, and feeling overly hungry.

They Provide Iron And May Help Prevent Anemia

The general consensus is that you can only obtain iron from animal foods, such as beef, eggs, and poultry. There are many plant-based foods, such as artichokes, that provide a good amount of iron. Iron deficiency is more common in women, especially premenopausal women, and children. Low levels of iron can cause fatigue, poor concentration, weak immune function, and digestive disorders. Ongoing low iron levels can lead to anemia, which occurs when the body cannot produce enough hemoglobin. As a result, red blood cells are not able to properly distribute oxygen throughout the body. That’s why eating iron-rich foods can help prevent anemia and other symptoms associated with iron deficiency. 

They May Improve Skin Health

If you do not consume enough vitamins C and E, the body cannot produce enough collagen. That may put you at risk for premature aging and other skin-related conditions. Artichokes supply these nutrients, in addition to other skin-nourishing antioxidants, that help fight free radicals that compromise skin health. The positive effects that artichokes have on the digestive tract also mean that they positively influence the immune system, which inadvertently helps the overall health of the skin. 

They May Help With Diabetes

Due to the high fiber levels, artichokes may help regulate blood sugar, which can help you avoid spikes and dips in insulin, which can be problematic for diabetics. The fiber in artichokes helps the body absorb glucose more slowly. Because the body does not digest fiber, it does not require insulin, so your fiber intake doesn’t count toward your total carb or glucose intake for the day. One randomized, double-blind, placebo-controlled trial investigated artichoke leaf extract in 80 patients with metabolic syndrome. After 12 weeks of supplementation, participants experienced significant reductions in fasting insulin levels, in addition to improved insulin resistance.

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Flavonoids might not be the first thing you think about when it comes to blood sugar, but they play a powerful role in supporting overall health – especially for those managing diabetes. These natural plant compounds are packed with antioxidants that help reduce inflammation, improve insulin sensitivity, and support healthy blood sugar levels. In simple terms: they help your body use glucose more efficiently and protect your cells from damage. You can find flavonoids in a variety of plant-based foods like berries, citrus fruits, apples, onions, kale, dark chocolate, and even green tea. The more colorful your plate, the more flavonoids you’re likely getting. Adding these foods into your daily routine isn’t just good for blood sugar – it also supports heart health, brain function, and overall wellness. Small changes in what you eat can lead to big changes in how you feel.

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Fatty liver CAN be reversed naturally – especially in the early stages. And no, it doesn’t require extreme dieting or medications. Your liver is one of the most resilient organs in the body. When you remove what’s overwhelming it and give it the right support, it knows how to heal. What actually helps:

• Losing just 5-10% of body weight
• Cutting added sugars & refined carbs
• Eating more whole, plant-based foods
• Moving your body consistently (even walking counts)
• Supporting insulin balance
• Prioritizing sleep & stress management

Foods matters. Lifestyle matters. Consistency matters. This isn’t about quick fixes – it’s about giving your liver the environment it needs to recover and thrive. Your body wants to heal. Support it.

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Get ready for a bright, lightly sweet, and refreshing juice made from grapefruit, carrots, and ginger root. Grapefruit’s tangy citrus bite is beautifully balanced by the earthy sweetness of carrots. Ginger root provides a subtly spicy kick and a warmth that helps enhance digestion and immune function. This simple combination of ingredients offers valuable nutrients, especially vitamin C, beat-carotene, and anti-inflammatory compounds. All of those nutrients together make this juice invigorating and supportive to overall health and wellness.

Grapefruit provides several key nutrients that are vital to immune function, heart health, metabolism, and liver support. Grapefruit is very rich in vitamin C, which encourages white blood cell production and collagen formation. Regarding heart health, the potassium in grapefruit helps regulate blood pressure, while the flavonoids work to reduce inflammation and enhance blood vessel function. Grapefruit also contains naringenin, which may reduce liver fat, aid detoxification pathways, and improve insulin sensitivity and glucose metabolism.

Carrots, much like grapefruit, work to support immune function, heart health, skin health, and gut health. They are naturally rich in beta-carotene, which converts to vitamin A in the body. Vitamin A is essential for night vision and maintaining healthy mucosal barriers. Finally, ginger contains key antioxidant compounds, including gingerol, shogaol, and zingerone. Researchers believe these compounds inhibit inflammatory pathways, helping to reduce muscle soreness and joint pain. They may also improve insulin sensitivity, improve gut motility, and encourage better circulation.

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Mounjaro, Ozempic, Wegovy, and countless other glucagon-like peptide-1 (GLP-1) medications are intended to help lower blood sugar levels. They work to trigger insulin release from the pancreas. Insulin lowers the amount of glucose in the blood, and insufficient insulin levels can cause blood sugar to increase and increase the risk of diabetes. That is not really why GLP-1 medications are so popular these days, though. People use these drugs to promote weight loss and control obesity. 

Glucagon is a hormone that the body uses to elevate blood sugar levels when necessary. GLP-1 actually prevents glucose from entering the bloodstream. It also slows stomach emptying, which ultimately releases less glucose from the food you eat into the bloodstream. GLP-1 medications also affect the area of the brain that processes hunger and satiety. You basically feel full quicker after eating a smaller amount. 

Given the popularity of these drugs, scientists question whether or not there is a natural way to tap into those same hunger- and fullness-pathways without drugs. A new review pulled emerging evidence on foods and plant compounds that may help support the body’s own GLP-1 activity. Just to be clear, though, these natural options are not replacements for medications. Early science does suggest that they may play a meaningful role in supporting appetite regulation and blood sugar balance. 

The Science Behind Natural GLP-1 Modulation

The review was recently published in Toxicology Reports and included decades of data on how foods, herbs, and bioactive compounds influence GLP-1, the hormone that GLP-1 drugs are designed to mimic. The gut produces GLP-1 and it has several jobs, such as:

• Stimulating insulin release
• Slowing digestion so you can stay fuller for longer
• Signaling fullness to the brain
• Reducing blood sugar after meals

GLP-1 medications work so well, so is it even possible for natural substances to gently support similar pathways? In order to figure this out, researchers looked at the combined research of studies on spices, teas, plant polyphenols, and fermented foods to see which compounds consistently influenced GLP-1 release or activity. As of now, nothing works as powerfully as prescribed medications; however, some ingredients triggered increases in GLP-1 release, or at least improved the body’s sensitivity to it. 

What The Researchers Found

According to the studies that researchers examined, the most natural GLP-1 supporters are as follows:

• Cinnamon extract
• Curcumin (from turmeric)
• Berberine
• Green tea and post-fermented tea compounds
• Wheat protein
• Ginger and gingerol
• Quercetin-rich plant foods (including apples, berries, cherries, onions, leafy greens, and grapes)

Researchers note that these natural GLP-1 modulators are not replacing existing medications. Instead, they want people to know that natural options exist. That helps because GLP-1 medications are not affordable or available to everyone. Some people also cannot tolerate the medications and experience intense side effects. Lastly, many people prefer nutrition-forward approaches to things. If you are looking to naturally support metabolic pathways, consider the ingredients we detailed. When paired with balanced nutrition and regular exercise, they may do wonders for your body.

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Hormones serve as chemical messengers that coordinate different functions within the body. There are several glands, organs, and tissues, which make up the endocrine system, that produce and release hormones. These hormones are vital for metabolism, growth, development, mood, and reproduction. 

What Do Hormones Do?

These chemical messengers affect and manage hundreds of bodily processes, many of which involve a chain reaction of several hormones. A hormone acts on a part of the body if it fits, e.g. the cells in the target tissue have receptors that can receive messages from that hormone. A hormone is like a key and the cells in the target tissues act as the lock. If the hormone fits the receptor on the cell wall, it will act appropriately and work, delivering a message that causes the target site to carry out a specific action.

The body uses hormones for two types of communication. The first type is between two endocrine glands, where one gland releases a hormone, stimulating another gland to change the levels of hormones that it is releasing. For example, this communication exists between the pituitary gland and the thyroid gland. The pituitary gland releases thyroid-stimulating hormone (TSH), which cues the thyroid to release its hormones that affect different bodily processes. The second type of communication is between the endocrine gland and a target organ. For example, the pancreas releases insulin, which acts on the muscles and liver to help produce glucose. 

Several studies support the fact that promoting a healthy microbiome can have a positive impact on hormonal balance. Consuming probiotics and a plant-rich diet may improve the body’s regulation of ghrelin, cortisol, and insulin. Read on to learn about foods that may help restore hormone balance. 

Flaxseeds

Flaxseeds contain lignans, which are a type of phytoestrogen that can mimic estrogen in the body. Researchers have studied them for their potential ability to reduce estrogen levels, particularly in regards to menopause and menstrual cycle irregularities. Flaxseeds are naturally rich in fiber, which may further support hormone balance by promoting a healthier microbiome. 

Leafy Greens

Swiss chard, kale, spinach, arugula, and other leafy greens contain a variety of vitamins, minerals, and antioxidants that support hormonal health. The antioxidants in leafy greens work to reduce inflammation and assist the body with hormone production. The iron content may also help prevent anemia, while the magnesium content may help the body regulate cortisol. That ultimately leads to a more balanced stress response. 

Berries

Not only are berries low in sugar, but they also contain a lot of antioxidants, which can help fight inflammation, a factor that contributes to hormonal imbalance. Strawberries, blueberries, raspberries, and blackberries may cause a slower and lower rise in blood sugar and insulin levels. Additionally, the fiber in berries helps maintain stable hormone levels by promoting optimal gut health. 

Avocados

Praised for their monounsaturated fats, avocados are always welcomed in your diet. Those monounsaturated fats play a crucial role in hormone production, as they serve as the building blocks for hormone synthesis. Avocados are also rich in fiber and magnesium, two nutrients that may help regulate estrogen and cortisol, respectively.

Quinoa

Technically a seed but grouped with whole grains, quinoa is a great source of complete protein, meaning it means all essential amino acids that the body does not make on its own. Those essential amino acids are necessary for bodily functions, including hormone production. Additionally, the complex carbohydrates in quinoa help slow digestion and nutrient absorption, contributing to more stable blood sugar levels. That ultimately helps balance the body’s insulin response. 

Lentils

Similar to other legumes, lentils are rich in fiber, which works to support balanced insulin levels and a healthy microbiome. Like quinoa, lentils are a great source of plant protein and have a low glycemic index, helping you maintain steady blood sugar. The B-vitamins and magnesium in lentils also support hormone production and function. 

Seaweed

Kelp and nori are a couple examples of seaweed that you can eat and they have the potential to influence estradiol levels in the blood. They may also increase the excretion of hormone-related substances in the urine, which can help balance all estrogen types. By potentially regulating estrogen levels and positively impacting gut bacteria, seaweed may be a great option for hormone health. 

Broccoli

Cruciferous vegetables such as broccoli and cauliflower are naturally rich in indole-3-carbinol. This compound supports the liver in metabolizing estrogen. Broccoli is also a great source of dietary fiber, which aids the regulation of insulin and other hormones.

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It’s no secret that new weight loss drugs are highly sought after in the United States. The reason for that is because they are highly effective, so long as you continue using them. Ozempic, Wegovy, Zepbound, Mounjaro, and other similar medications work by recreating the effects of GLP-1, a hormone that the gut produces once you finish eating. This hormone reduces both hunger and cravings, helping you to eat less, which promotes weight loss. 

What happens when you stop taking these medications, though? Recent research suggests that you can regain weight once you stop taking them. Health experts have started to refer to this weight gain as “Mounjaro plateau” or “Ozempic rebound.”

Why Do People Stop Using These Medications?

People stop taking these medications for numerous reasons, with a common one being the high cost, which is especially true for people without health insurance. Even if you have health insurance, many providers don’t offer coverage for these drugs. There is a huge demand, supply issues, and many unwanted side effects that come from using these medications. In fact, clinical trials found that up to 10% of users stop using these medications because of side effects, including nausea and disruptive bowel movements. 

It’s possible that the number of people who stop using these medications is higher than that 10% figure. Patients may have less aftercare, support, and accountability than they do in clinical trials. That means there is most likely a higher percentage of people who experience unwanted side effects, which could be easily managed. Doctors also state that people stop using these medications once they meet their goal weight. 

Why Do You Gain Weight Post-Medication?

Ozempic, and other related drugs, were originally intended to help people with type 2 diabetes manage blood sugar levels. During clinical trials, researchers observed weight loss to be a surprising side effect. That got them thinking, so they started to prescribe these medications for weight loss (an off-label purpose). 

In present day, many people with high blood pressure, type 2 diabetes, high cholesterol, or fatty liver disease, have been struggling to lose weight for 20 to 30 years. Drugs like Ozempic or Wegovy help people lose weight by temporarily altering hunger mechanisms. Basically, they provide a synthetic form of GLP-1, which is the hormone that helps you feel satiated and less hungry. At the same time, these drugs also promote an increase in insulin response to food, which works to regulate blood sugar. They also reduce the release of glucagon, a hormone that opposes insulin and tends to increase blood glucose levels. 

When you stop taking these medications, the body naturally produces more ghrelin, the hunger hormone. Once off the medications, the body’s metabolic rate slows down. The combination of a slower metabolic rate and a rapid onset of hunger causes weight gain, especially if there is no modification in lifestyle or diet. 

How Common Is Weight Gain After Stopping Ozempic?

If you use Ozempic to lose weight, the last thing you want is to see the weight return once you stop taking the drug. As it turns out, it is very common for a person to gain weight after quitting Ozempic or similar medication. One study found that people who stopped taking semaglutide (the active ingredient in Ozempic) and quit lifestyle interventions gained two-thirds of their weight back within a year. Another study monitored people who stopped taking tirzepatide, the active ingredient in Zepbound and Mounjaro. Within one year of quitting the drug, they gained more than half the weight they’d lost while on the drug. 

The Takeaway

Before you take any GLP-1 agonist (such as Ozempic), consult your healthcare professional and make sure you understand the risks. Are you using the drug for short-term or long-term results? If you decide to take Ozempic, make sure you understand what will happen once you stop. Your healthcare professional may be able to provide guidance, nutritional advice, and an exercise regimen to help stave off the weight you lost while on the drug.

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GLP-1 medications, such as Ozempic and Wegovy, have been referred to as weight loss “game-changers” or “miracles” for people living with obesity. A 2021 clinical trial found that 86.2% of more than 800 participants experienced significant weight loss after taking 2.4-milligram (mg) doses of semaglutide for 68 weeks. While that sounds promising, 13.8% of participants did not see clinically significant weight loss. 

When it comes to GLP-1 medications, health experts state that people fall into two camps: responder or non-responder. The former indicates that people positively respond to the medications and experience weight loss, while the later indicates that the medications have no effect on the person. Just like with other medications, one prescription is not a one-size-fits-all remedy for every single person. That is especially true for managing obesity. 

Doctors want to remind patients that there tends to be more than one reason why a person ends up in the responder or non-responder categories. Even though the drugs may seem ideal in clinical trials, they do not work for everyone. Just like other medications, they can be unpredictable, both in how they perform and how a person responds to them. Why is that the case? Continue reading to learn about five of the most common reasons, according to health experts. 

Existing Medical Issues

It’s possible for a person to have underlying medical issues that are either untreated, undertreated, or undiagnosed. Hypothyroidism, sleep apnea, and chronic insomnia, for example, can all interfere with weight loss. Those conditions should be dealt with prior to starting a weight loss journey, let alone a weight loss medication. Patients who have an issue with obesity and a binge eating disorder should also address the eating disorder prior to using GLP-1 medications. The binge eating disorder will not correct itself just because you take a GLP-1. 

Medication Interference

People who take GLP-1 drugs alongside other medications may experience less weight loss, or none at all. It’s common for people who take antidepressants and beta blockers to have a difficult time losing weight. Adding a GLP-1 drug to the mix will not encourage weight loss, though. It is better to speak to your healthcare provider about other medications prior to taking a GLP-1. 

Insulin Resistance 

Ozempic is a GLP-1 drug designed to help diabetics lower their A1C. According to a 2022 narrative review, though, people may lose less weight while taking GLP-1 medications. When you have a pre-existing metabolic disease, it can feel like an uphill battle to reverse those abnormalities, especially if you’ve lived with them for a long time. This is due to the physiological response. Typically, GLP-1 aids blood sugar control by stimulating the pancreas to release insulin after meals. That response may be less potent in individuals who do not have type 2 diabetes. The weakened response to GLP-1, then, can make it more difficult to manage blood sugar and lose weight, which can require alternative treatment methods. 

Lifestyle Changes

Trials for semaglutide have included lifestyle intervention for both placebo and medication groups. In a 2021 trial consisting of more than 1,900 adults, for example, researchers wanted to see what influenced the best response to a GLP-1 medication. The general recommendation was that patients should:

• Exercise regularly
• Manage stress
• Maintain a predominantly plant-based diet
• Get quality sleep
• Avoid substance use
• Keep strong social relationships with family and friends

Now, those recommendations are not novel in regards to losing weight and living healthier. In fact, those are things that you should do if you want to be healthier and lose weight. It’s possible that some of these efforts can interfere with GLP-1 medications or reduce their efficacy, but more research is necessary on this matter.

What If You Don’t Experience Weight Loss?

Sometimes, you may not experience weight loss immediately after starting GLP-1 medications. Some people have to take the medication for up to 12 weeks before seeing results. If you have doubts about this, or see that these medications are not moving the needle, consider speaking with your doctor or engage in some of the previously mentioned lifestyle changes. 

You can also consider the Dherbs Full Body Cleanse, which is a 20-day program that has helped millions of people lose weight and experience better overall health. It outlines exactly what you need to do to succeed during the cleanse. Although a lot of people use the cleanse to lose weight (potential to lose 10 to 30 pounds during the 20-day cleanse), its main purpose is to cleanse the body’s major organs and systems. Using the Full Body Cleanse can help the pounds go down and improve overall health and wellness. Not to mention, it’s about one-tenth the cost of GLP-1 medications!

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Berberine is a naturally occurring compound in many plants. For thousands of years, it has been used in Traditional Chinese Medicine (TCM), Ayurveda, and other medicinal traditions to treat digestive disorders, inflammatory conditions, and infections. Some research indicates that it may offer protection against high blood pressure, diabetes, and high cholesterol, among other conditions. 

What Is Berberine?

Extracted from several plants, berberine is a bioactive compound that belongs to the alkaloid class. It is yellow and typically used as a dye, despite its long history in traditional medicinal applications. Modern evidence suggests that it exhibits impressive health benefits that may address chronic conditions. As of now, limited human research indicates that berberine may lower cholesterol, triglycerides, and blood sugar levels. This is of great interest to the health experts because these are reversible risk factors for heart disease. Although it appears to be safe and only causes a few mild side effects, you may want to consult a healthcare professional if you are interested in taking it. 

How Does Berberine Work?

There have been hundreds of studies on berberine’s effects on the body. According to animal studies, one of berberine’s primary actions is to activate AMP-activated protein kinase (AMPK), an enzyme inside cells. Found in cells throughout the body, AMPK has an active role in regulating metabolism and energy levels. Berberine also has an effect on other molecules inside cells, potentially affecting which genes are turned on or off. That may help protect against many chronic health conditions, but more research is necessary on this matter. Continue reading to learn more about berberine’s health benefits. 

May Protect Against Bacterial Infections

A 2022 study found that berberine helped prevent the growth of Staphylococcus aureus. Researchers note that this bacterial strain can cause sepsis, pneumonia, meningitis, and a range of skin conditions. Another study found that berberine exhibited an ability to damage the DNA and protein of certain bacteria, due to its antimicrobial activity. 

It Helps Lower Blood Sugar Levels

According to many studies, berberine can significantly lower blood sugar levels in people with type 2 diabetes. In 2008, study authors monitored a group of 116 participants who took one gram of berberine per day. The results indicated that berberine lowered fasting blood sugar by 20%, and it also lowered hemoglobin A1c (HbA1c) by 12%. Additionally, berberine improved blood lipids, including cholesterol and triglycerides. Researchers note that berberine seems to work in several ways to aid these processes:

• Decreases sugar production in the liver
• Reduces insulin resistance to make insulin more effective
• Increases the amount of beneficial bacteria in the gut
• Slows the breakdown of carbohydrates in the gut
• Increases glycolysis, which helps the body break down sugars inside cells

May Aid Weight Loss

There is a lot of attention on berberine because it may be a viable weight loss supplement. An older 12-week study involved people with obesity who took 500 milligrams (mg) of berberine three times daily. At the end of the study, participants experienced five pounds of weight loss, on average, with a 3.6% reduction in body fat. A review of 12 studies noted that supplementing with berberine led to significant reductionist body weight, belly fat, and body mass index. It was also effective at decreasing C-reactive protein, a marker of inflammation. Other research found that berberine works to inhibit the growth of fat cells at a molecular level, which may promote weight loss. Although existing research is promising, more research is necessary to determine berberine’s weight loss effects.

It Helps Lower Cholesterol

If you have high levels of triglycerides and LDL cholesterol, you have a higher risk of heart disease and stroke. Some research suggests that berberine may help lower LDL cholesterol and triglyceride levels. One review of both animal and human studies found that berberine exhibits cholesterol lowering effects. Researchers believe that berberine’s effects are similar to drugs that reduce high cholesterol. The only difference is that berberine does not cause the same side effects. 

May Benefit People With Obesity

There is an obesity epidemic in the United States, and it increases a person’s risk of type 2 diabetes, heart disease, high cholesterol, and high blood pressure. One review found that people who took 750 mg of berberine twice daily for three months experienced significant weight loss. Another double-blind study monitored people with metabolic syndrome who took 200 mg of berberine three times daily. Participants experience decreases in their body mass index scores. Finally, some research suggests that berberine works similarly to metformin, a drug that doctors typically prescribe people with type 2 diabetes. Additionally, berberine works to alter gut bacteria, which may benefit people with diabetes and obesity.

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Is there anything better than a good night’s sleep? You wake up in a good mood and when you sit up and get out of bed, it’s as though your body thanks you for that rest. Contrast to the mornings when you wake up after a minimal amount of sleep. You don’t feel like yourself and you usually see dark circles under your eyes. You feel sluggish and would give anything for a few more hours of sleep. 

Growing evidence indicates that sleep is necessary for maintaining long-term health. The body can typically handle a few nights with minimal sleep, but it is not sustainable over time. There will be a price you pay if you continually get insufficient sleep, according to health experts. In this article, we’ll detail some of the health problems linked to sleep deprivation.

Type 2 Diabetes

People who experience minimal sleep or poor quality sleep tend to have poorer blood sugar control, especially in people with diabetes. Additionally, sleep deprivation can increase the risk of developing type 2 diabetes, according to some studies. In a group of middle-aged Caucasians, researchers observed a strong connection between poor sleep quality and metabolic syndrome, fasting blood duster levels, insulin levels, and insulin resistance, a precursor for type 2 diabetes. 

Kidney Issues

Unfortunately, the link between insufficient sleep and kidney health has not been as firmly established as the link between poor sleep and other health conditions. Researchers note that people with chronic kidney disease tend to have sleep disorders, including restless leg syndrome and insomnia related to their condition. Some evidence shows that poor sleep quality may increase the risk of developing chronic kidney disease. Researchers believe that the link could be related to disruptions to the circadian rhythm. 

Depression And Anxiety

According to research, people who have chronic insomnia have a higher rate of depression and anxiety. An estimated 40% of people with insomnia have clinical depression. The relationship between your mood and sleep is complex and bidirectional. That means that depression or anxiety can negatively impact sleep and lack of sleep can negatively affect your mood. Sleep experts consider insomnia to be an independent risk factor for developing mental health disorders, such as depression. You may need to address your sleep problems and anxiety or depression separately in order to improve your overall health. 

A Less Healthy Gut

The gut microbiome is a complex system of trillions of microorganisms found in the gastrointestinal (GI) tract. Experts believe that the more diverse the microbiome, the better a person’s overall health is. Some studies suggest that altered sleep patterns, such as those consistent with night shift workers, may impact gut health. One study used Mendelian randomization, a method that looks at genetic variation to study the effects of different health variables. This study found that sleep issues may alter the abundance of bacteria in the gut. 

Hypertension, Stroke, And Heart Disease

According to the American Heart Association (AHA), the smallest changes in sleep have been linked to heart issues. After the clocks change in March, there are 24% more heart attacks for the first three to four days. When the clocks “fall back” in November, the AHA estimates a 21% reduction in heart attacks because people gain an hour of sleep. Sleeping for five hours or less per night on a regular basis has been associated with a two to three times greater risk of coronary artery buildup. That decreases the flow of blood to your heart, so sleep deprivation may increase the risk of coronary artery disease. 

Reduced Immune Function

Sleep experts suggest that insufficient sleep or poor sleep quality can harm immune function. Evidence shows that poor sleep increases your susceptibility to various infections and illnesses. Studies show that people who sleep less than seven hours per night are three times more likely to develop the common cold compared with people who get eight hours or more of sleep per night. 

Additional research states that insufficient sleep can make it more difficult for the body to produce disease-fighting antibodies, specifically after receiving flu, hepatitis A, and hepatitis B vaccines. Participants who only slept four hours per night in the days before and following vaccination developed lower levels of antibodies compared to those who had great sleep. 

Weight Gain

Unfortunately, there is a strong connection between sleep issues and being overweight or having obesity. Failure to get enough sleep every night can cause a hormonal imbalance, and these are the hormones that regulate appetite. Ghrelin makes you feel hungry and leptin helps you feel full. Leptin levels tend to rise during sleep, so the theory is that insufficient sleep causes a decrease in those levels. That makes you feel hungrier, which leads to unnecessary eating. Additionally, sleep disturbances of any kind can increase the production of ghrelin, which increases appetite. Studies suggest that insufficient sleep can make people burn 100 more calories per day. While that sounds wonderful, the extra wake time increases how much people eat or drink by more than 250 calories per day. Over time, that can cause people to gain weight.

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