If you have hypertension (high blood pressure), management is key in order to minimize your risk of heart attack or stroke. In order to manage high blood pressure, you have to avoid or limit certain foods, in addition to supplements, as they can affect blood pressure, or make matters worse. 

High blood pressure is characterized by a blood pressure reading of 130/80 mm Hg or higher. Older adults have a higher risk of the condition, due to large arteries getting stiffer with age. If you cannot control blood pressure on your own with lifestyle changes, medication may be necessary. The American Heart Association (AHA) estimated that 46% of American adults have high blood pressure. Should you have the condition, avoid the supplements in this article. 

Licorice Root

Licorice root is not solely used as a flavoring in food, candy, and even tobacco products. In fact, it has a long history of use in folk medicine, treating wounds and relieving symptoms of lung disease and liver disease. Licorice root contains glycyrrhizic acid (GA), which can elevate blood pressure. Researchers note that doses as low as 100 milligrams (mg) can raise blood pressure. Other supplements with GA can also interact with diuretics and blood pressure meds. It may affect how well blood pressure meds work and increase the risk of side effects. If you have high blood pressure, it is best to avoid products that contain licorice root. 

Arnica

Some people use arnica ointment to reduce swelling and bruising, while others take it orally as a supplement. Arnica belongs to the sunflower family and is usually taken by mouth homeopathically. There are typically no. active ingredients in homeopathic products, so side effects are unlikely. That said, taking arnica by mouth can increase blood pressure or potentially damage some organs, including the heart. This is not for certain, but if you have high blood pressure, avoid arnica supplements. 

Bitter Orange

Taken from the fruit or peel of a bitter orange, this supplement is typically used to aid weight loss or improve athletic performance. The fruit and peel of bitter orange can also be used to flavor drinks or in perfumes and other beauty products for aromatic purposes. Bitter orange does contain p-Synephrine, which is a type of stimulant similar to ephedrine. The U.S. Food and Drug Administration (FDA) banned ephedrine stimulants because they can cause health issues, such as heart attack and stroke. Although bitter orange is not on a banned list, use it with caution, especially if you have high blood pressure. Studies show that this supplement can not only raise heart rate and blood pressure, but also increase the risk for heart attack and stroke. Bitter orange found in food and drinks is not likely to cause these issues, though. 

Vitamin D (In High Doses)

The body produces vitamin D when the skin is exposed to ultraviolet (UV) rays from the sun. Vitamin D is necessary for optimal bone health, inflammation reduction, and other bodily functions. It is naturally available in foods and supplement form. Some research indicates that vitamin D may play a role in treating high blood pressure, specifically in doses of 200 – 8,000 International Units (IU) per day. Doses larger than 10,000 IU per day can lead to dangerous side effects, such as high calcium levels (hypercalcemia). Over time, hypercalcemia can cause high blood pressure. High doses of vitamin D can also interact with certain diuretics, which are commonly used to treat high blood pressure. The body may not get rid of enough calcium, raising calcium and blood pressure in the process. 

St. John’s Wort

This plant is often used to treat symptoms of menopause and depression. Despite its longstanding use in traditional medicine, this plant may negatively interact with a variety of medications. St John’s wort weakens the efficacy of medications used to treat high blood pressure. Some of the blood pressure meds that St. John’s wort interacts with include Talinolol, Verelan, and Procardia. The interactions are likely due to the fact that St. John’s wort blocks the medication from being absorbed by the body.

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Various studies indicate that cinnamon is rich in antioxidants, but it isn’t the only superfood in the spice drawer. There are other spices, which you should not overlook, that offer potent antioxidant compounds. Some of these compounds may help boost immune function, fight inflammation, and reduce oxidative stress, which can contribute to chronic health conditions. 

What Are Antioxidants?

In simple terms, antioxidants are molecules that assist the body with fighting off harmful free radicals, which the body naturally produces. Ultimately, “antioxidant” is a general term for any compound that counteracts unstable molecules (free radicals) that damage DNA, cell membranes, and cell parts. Antioxidants help control the amount of free radicals in the body, helping lower the risk of health conditions such as cancer and diabetes. You can find antioxidants in many foods, and several vitamins, such as vitamins C and E, are powerful antioxidants.

Turmeric

One of the best anti-inflammatory spices is turmeric, and it is largely because of the active compound: curcumin. Not only does it work to lower oxidative stress and support immune function, but it also supports inflammation pathways in the body. Although curcumin has been linked to improvements in arthritis, anxiety, and metabolic syndrome, more research is necessary. Ground turmeric powder offers the most concentrated antioxidants, but make sure to pair it with black pepper and a fat source to make curcumin more bioavailable. If you are on blood thinners or other medications, consult your doctor before you take turmeric because it can interfere with some medications. 

Ginger

Ginger adds a zesty zing to any sauce, smoothie, or stir fry, and the tea has just enough spice to help soothe a sore throat. Both fresh and ground ginger offer benefits, but fresh ginger root brings more aromatic compounds. According to research from 2020, ginger can trigger the release of anti-inflammatory messenger proteins called cytokines while simultaneously reducing pro-inflammatory ones. The specific antioxidant compound behind this ability is gingerol, which gives ginger its warm, bright flavor. Studies show that when ginger is dried, the gingerols convert to shogaols, which can be more potent, according to lab studies. Both gingerols and shogaols may have anti-inflammatory and anti-tumor properties. 

Cloves

Laboratory measures of a specific food’s antioxidant content do not reveal how the body absorbs or uses them. Ground cloves, however, have a higher Oxygen Radical Absorbance Capacity (ORAC) than cinnamon, according to nutritional data. The antioxidants in cloves include flavonoids, gallic acid, and eugenol. A 2025 study found that the antioxidants from clove pods could be more effective in lower doses when compared to other antioxidants, such as beta-carotene and ascorbic acid. Eugenol also binds strongly to bacterial enzymes, meaning it may have antibacterial properties. Cloves may also help decrease blood clotting and blood sugar, but may be harmful in high doses. 

Oregano

A classic spice in many different cuisines, oregano is rich in flavonoids and other antioxidants, including thymol and carvacrol. Studies suggest that these antioxidants may support immune function. In fact, as an essential oil, oregano has exhibited powerful antimicrobial and anti-fungal properties. Oregano may also support intestinal wellbeing, helping to fight bad bacteria in the gut and balance overall gut bacteria. Due to oregano’s potency, exercise caution when using it. As a supplement, oregano is very strong and should only be used under medical supervision. If you use oregano oil, use it in the short-term, as long-term use can disrupt gut microbiome.

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Mounjaro, Ozempic, Wegovy, and countless other glucagon-like peptide-1 (GLP-1) medications are intended to help lower blood sugar levels. They work to trigger insulin release from the pancreas. Insulin lowers the amount of glucose in the blood, and insufficient insulin levels can cause blood sugar to increase and increase the risk of diabetes. That is not really why GLP-1 medications are so popular these days, though. People use these drugs to promote weight loss and control obesity. 

Glucagon is a hormone that the body uses to elevate blood sugar levels when necessary. GLP-1 actually prevents glucose from entering the bloodstream. It also slows stomach emptying, which ultimately releases less glucose from the food you eat into the bloodstream. GLP-1 medications also affect the area of the brain that processes hunger and satiety. You basically feel full quicker after eating a smaller amount. 

Given the popularity of these drugs, scientists question whether or not there is a natural way to tap into those same hunger- and fullness-pathways without drugs. A new review pulled emerging evidence on foods and plant compounds that may help support the body’s own GLP-1 activity. Just to be clear, though, these natural options are not replacements for medications. Early science does suggest that they may play a meaningful role in supporting appetite regulation and blood sugar balance. 

The Science Behind Natural GLP-1 Modulation

The review was recently published in Toxicology Reports and included decades of data on how foods, herbs, and bioactive compounds influence GLP-1, the hormone that GLP-1 drugs are designed to mimic. The gut produces GLP-1 and it has several jobs, such as:

• Stimulating insulin release
• Slowing digestion so you can stay fuller for longer
• Signaling fullness to the brain
• Reducing blood sugar after meals

GLP-1 medications work so well, so is it even possible for natural substances to gently support similar pathways? In order to figure this out, researchers looked at the combined research of studies on spices, teas, plant polyphenols, and fermented foods to see which compounds consistently influenced GLP-1 release or activity. As of now, nothing works as powerfully as prescribed medications; however, some ingredients triggered increases in GLP-1 release, or at least improved the body’s sensitivity to it. 

What The Researchers Found

According to the studies that researchers examined, the most natural GLP-1 supporters are as follows:

• Cinnamon extract
• Curcumin (from turmeric)
• Berberine
• Green tea and post-fermented tea compounds
• Wheat protein
• Ginger and gingerol
• Quercetin-rich plant foods (including apples, berries, cherries, onions, leafy greens, and grapes)

Researchers note that these natural GLP-1 modulators are not replacing existing medications. Instead, they want people to know that natural options exist. That helps because GLP-1 medications are not affordable or available to everyone. Some people also cannot tolerate the medications and experience intense side effects. Lastly, many people prefer nutrition-forward approaches to things. If you are looking to naturally support metabolic pathways, consider the ingredients we detailed. When paired with balanced nutrition and regular exercise, they may do wonders for your body.

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Last week, over half a million bottles of prazosin hydrochloride, a blood pressure medication, were recalled by drug manufacturer Teva. The reason for the recall was because testing revealed higher-than-acceptable levels of impurities known as N-nitrosamines. All of this information was released by the U.S. Food and Drug Administration (FDA) via an enforcement report.

The enforcement report detailed a Class 2 event, indicating that the affected medications, “…may cause temporary or medically reversible adverse health consequences or where the probability of serious adverse health consequences is remote.” The recall is for 1, 2, and 5 milligram (mg) doses of prazosin hydrochloride. This medication is an alpha-blocker that is FDA-approved to help treat high blood pressure. Some people also use prazosin hydrochloride to treat benign enlarged prostate, nightmares related to PTSD, and temporary discoloration in the extremities due to cold exposure. 

You can check the lot number on your prescription to see if it was included in the FDA’s list. The FDA and Teva did not indicate whether consumers should throw out prazosin included in this recall. For the Class 2 recalls, however, the FDA states that people can typically keep taking the recalled medications unless otherwise stated by the manufacturer. That is entirely your decision to make, as stopping medication in certain instances may be more harmful. Consult your doctor or pharmacist if you have questions regarding your medication. 

What Are N-Nitrosamines?

These chemicals commonly exist in water and foods, including cured and grilled meats, dairy, and vegetables. Most people are exposed to some amount of nitrosamines, but that depends on diet and other factors. 

The N-nitrosamine impurities can form during the manufacturing or storing processes of a drug. According to the FDA, the N-nitrosamine impurities may increase the risk of cancer if people are exposed to them above acceptable levels and over long periods of time. If you happened to take a medication with nitrosamine levels at or below accepted levels, every day for 70 years, you wouldn’t be expected to have a higher cancer risk. As that is an estimation, you may not want to take that chance. 

At Dherbs, we are not medical professionals, so we cannot legally advise how you should proceed with this current recall. If you do take this specific blood pressure medication, though, consult your doctor or pharmacist if you have not received any information from the manufacturer. We are always here to help you improve your health and we encourage you all to do your research regarding not only our products, but anything that you decide to put in your body.

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Pooping is something everyone does on a daily basis, ideally once or twice per day, but nobody wants to talk about it. We love to talk about it! If you aren’t eliminating on a regular basis, then something is going on, be it poor eating habits, insufficient exercise, stress, or a digestive problem. Whatever the case may be, it can be quite frustrating (and painful) if you cannot poop.

According to available data, constipation affects 18% of adults in the United States. It is a common issue that people of all ages can experience and it has various causes. Lack of fiber, delaying bowel movements, traveling, certain medications, and hormonal changes can all cause constipation. It can also be a symptom of other health conditions and some common symptoms include:

• Fewer than three bowel movements per week
• Hard, dry, or lumpy stools
• Straining during bowel movements
• Bloating or abdominal pain
• Feeling like you still need to eliminate after using the toilet

What you eat can have a big impact on digestive function. Certain foods can also help you improve symptoms of constipation. Foods that are naturally rich in fiber, fluids, and natural laxatives can make stool easier to eliminate. Enjoy the following foods to help stimulate bowel movements. 

Mangos

The mango is a juicy, tropical fruit that is a staple in many smoothie, dessert, and salad recipes. You can also cube it up to use it as a topping for acai bowls or chia pudding recipes. According to several studies, mangos can aid with constipation relief. Mangos are naturally rich in fiber, which adds bulk to stool, allowing it to move more easily through the digestive system. One study found that participants who ate 300 grams of mango (about one to two mangos) per day over four weeks saw an improvement in constipation. 

Kiwi

As a vitamin C superstar, kiwi is an excellent fruit to help boost immune function. It may also be an effective constipation remedy, as it is naturally rich in soluble and insoluble fiber. Soluble fiber helps optimize gut microbiome, while insoluble fiber helps maintain regular bowel movements, but you can click here to learn more about the difference between them. Several studies indicate that kiwis work to improve complete spontaneous bowel movements (CSBMs), bowel habits, and transit time. Researchers attribute the constipation relieving abilities to the fiber content in kiwis. Another study found that eating two kiwis per day can reduce abdominal discomfort and improve constipation. 

Figs

These soft, sweet, fruits are not for everyone, but they do help relieve symptoms of constipation. They are less popular than apples and prunes for improving bowel movements, but studies show that fig paste can improve transit time and stool consistency. One study monitored people with irritable bowel syndrome (IBS) who ate four dried figs per day reported a decrease in symptoms of constipation, including hard stools, compared to those who ate a placebo. 

Apples

According to surveys, apples are the most consumed fruit in the United States. They are naturally rich in pectin, a type of soluble fiber that works to improve the transit time of food in the digestive system. Pectin helps to absorb water in the digestive tract, which creates larger, softer stools that are easier to eliminate. Researchers note that supplementing with pectin can increase colon transit time and decrease constipation symptoms. 

Prunes

Potentially one of the most effective constipation remedies, prunes are rich in fiber and sorbitol, making them a natural laxative that can stimulate bowel movements. Studies indicate that prunes significantly improve stool consistency and increase the number of CSBMs when compared to psyllium, another form of soluble fiber that is occasionally used as a laxative. 

Psyllium

To round out the list of foods that help you poop, we have psyllium. Psyllium can come in husk or powder form, and supplement manufacturers use it in laxatives because it increases the bulk of stool. It does this by drawing in water to ease the passage of stool. According to several studies, psyllium can reduce straining, improve stool frequency and consistency, and reduce stomach pain. Although psyllium isn’t as effective as prunes, it is a natural laxative to experiment with if you have a prune allergy. 

Still need a little help encouraging a bowel movement? Consider our Bowel Motion formula, which contains herbs designed to alleviate bloating and gas. It also stimulates peristalsis and helps maintain regular bowel movements.

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Saw palmetto (Serenoa repens) is a type of palm that is native to the southwestern United States. It is commonly used in various supplements to improve prostate health, prevent hair loss in men, and balance hormone levels. Saw palmetto has actually been marketed as a natural remedy for an enlarged prostate. In fact, more than a third of all adults in the U.S. who take saw palmetto supplements do so specifically to improve prostate health. 

Although more research is needed on saw palmetto’s effect on men’s health, the existing research shows great promise. Some people, including those who may be pregnant, should avoid saw palmetto. Continue reading to learn about the top four benefits of saw palmetto.

May Support Prostate Health 

The prostate gland is located between the bladder and the penis. It is responsible for maintaining sperm health, but an enlarged prostate can get in the way of healthy urinary flow and sperm production. According to various research studies, saw palmetto can support prostate health and help prevent issues, such as benign prostate hyperplasia (BPH) and prostate cancer. Other studies indicate that saw palmetto may reduce BPH-related urinary symptoms and inflammation. One 15-year study of 30 participants with BPH found that 320 milligrams (mg) of saw palmetto extract per day may help prevent the progression of BPH. 

May Reduce Inflammation

There are numerous animal studies that suggest that saw palmetto exhibits anti-inflammatory activity, which may benefit certain health conditions. One study from 2015 in rats with BPH found that saw palmetto effectively decreased inflammation and improved antioxidant status. A separate 2015 study in mice with enlarged prostates found that saw palmetto extract decreased several inflammatory markers, including interleukin 6 (IL-6). Although these studies are promising, research on humans is lacking. For this reason, there isn’t enough scientific evidence to claim that saw palmetto reduces inflammation in humans. 

May Improve Urinary Tract Function

It’s possible that saw palmetto may benefit BPH, which is a condition that causes an enlargement of the prostate gland, leading to decreased urine flow. A small 12-week study including participants with BPH found that those who took 1,000 mg of saw palmetto oil mixed with beta-sitosterol experienced significant improvements in BPH symptoms. Another 24-week study of 354 participants found that supplementing with 320 mg of saw palmetto decreased BPH symptoms and improved urinary flow and sexual function. More research is still necessary to determine whether saw palmetto supplements aid urinary tract function in the general population. Current research is promising, though. 

May Help Regulate Testosterone Levels

Many people who want to naturally boost testosterone levels may turn to saw palmetto oil as an option. Testosterone affects body composition, sex drive, mood, brain function, and more. Testosterone levels naturally decline naturally with age and can interfere with quality of life. Some research suggests saw palmetto may boost testosterone levels by decreasing the activity of 5-alpha reductase, an enzyme that converts testosterone to DHT, to help preserve testosterone. A 2020 review found that saw palmetto may also block the uptake of DHT and reduce its ability to bind to androgen receptors by almost 50%. A smaller and older study found that supplementing with 1,200 mg of Resettin, a supplement containing saw palmetto and astaxanthin, increased serum testosterone levels by 38%. Looking to boost testosterone levels, consider the Dherbs Testosterone Booster as a natural alternative. 

May Prevent Hair Loss

Hair loss is very common among men and has numerous causes, from genetics and hormonal changes to certain medications and health conditions. Some people tend to use saw palmetto to balance hormone levels and reduce hair loss. As previously mentioned, saw palmetto may block 5-alpha reductase, which is linked to hair loss. By reducing the uptake of DHT in your hair follicles, saw palmetto may help decrease DHT’s ability to bind to specific hormone receptors. A 16-week study from 2023 involving people with androgenic alopecia who took a specifically formulated saw palmetto supplement found that saw palmetto reduced the rate of hair falling out. It also contributed to hair growth and improved scalp appearance compared to a placebo.

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Wormwood sounds like an herb that you would receive from a shaman during a medieval quest. Believe it or not, wormwood is one of the three key ingredients in absinthe, which Pablo Picasso, Edgar Degas, and Vincent Van Gogh used to drink. Maybe that’s why they were such incredible artists!

What Is Wormwood?  

Wormwood, known scientifically as Artemisia absinthium, helps to eliminate intestinal worms, specifically roundworms and pinworms. The plant, which is native to Europe, Asia, and North Africa, has a bitter taste and has been used for centuries in medicinal applications. Researchers note that wormwood is a perennial herb that exhibits a wide range of health benefits. Continue reading to learn about six of the many impressive health benefits of wormwood.

Aids Digestion

According to historical evidence, wormwood has helped treat flatulence, indigestion, gastritis, and other digestive issues. Wormwood contains bitter compounds that stimulate the production of digestive enzymes, which enhance the absorption of nutrients from the foods you eat. The terpenes in wormwood also stimulate saliva, stomach mucus, and intestinal secretions, all of which may ease digestive symptoms. Wormwood may also reduce stomach acids that contribute to acid reflux and peptic ulcers. 

It Exhibits Anti-inflammatory Properties

Wormwood contains artemisinin, a compound that researchers believe to have potent anti-inflammatory properties. A few studies suggest that wormwood may also temper the actions of cytokines, which are proteins that help instigate inflammation. In doing so, wormwood may ease redness, warmth, swelling, and other symptoms of inflammation. Most of the research about wormwood’s anti-inflammatory properties have been focused on people with osteoarthritis or rheumatoid arthritis. A 2016 study monitored people who took 150 milligrams of wormwood extract per day for 12 weeks. The results indicated that they experienced less joint pain than the group that took a placebo. 

It Has Antimicrobial and Anti-parasitic Effects:

Wormwood has exhibited potent antimicrobial properties against many pathogens, from bacteria to fungi, and even parasites. Studies show that wormwood is most effective when it comes to eliminating pinworms and roundworms from the body. Other studies found wormwood to be effective against gut parasites like Giardia lamblia and Helicobacter pylori. For these reasons, wormwood may be a promising natural alternative to traditional anti-parasitic medications or drugs.

Enhances Liver Function

Historically, wormwood was used to help support liver function. Wormwood contains compounds that help promote the secretion of bile, aiding in the breakdown of fats and toxins. Reports suggest that regular consumption of wormwood may help detoxify the liver, which helps protect it from free radical damage.

May Fight Cancer Cells

Several studies found that the artemisinin compound in wormwood may fight against iron-enriched breast cancer cells. It actually fights these cancer cells the same way it eliminates malaria-causing parasites. Cancer cells can be rich in iron because they soak it up, which facilitates cell division. A 2012 study tested samples of breast cancer cells and normal breast cells that had been treated to maximize iron content. After that, the cells were treated with a water-soluble form of artemisinin. Results revealed that normal breast cells showed little change. Within 16 hours, however, the cancer cells were dead, with only a few normal cells killed. 

May Offer Pain Relief

In the past, wormwood was used in herbal remedies as a pain-reliever. Because it contains analgesic properties, wormwood may alleviate various forms of discomfort, including headaches, menstrual cramps, and muscle pain. Researchers don’t fully understand the mechanisms behind these effects, so more research is necessary.

Precautions

Although wormwood offers a variety of health benefits, it is crucial to exercise caution when using it. Because wormwood contains thujone, a compound that can be toxic if consumed in excessive amounts, there are certain people that should avoid it. Pregnant women, individuals with seizure disorders, and those with liver disease should not consume wormwood. Should you want to incorporate wormwood into your diet, consider speaking with a healthcare professional, especially if you have a health condition or take specific medications.

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There are many semaglutide and tirzepatide (known commercially as Ozempic, Wegovy, Zepbound, and Mounjaro) on the market. These drugs target GLP-1 receptors and have been influential in the treatment of diabetes and obesity. Many people can experience dramatic weight loss and benefits for other chronic health conditions. At the same time, these medications come at a steep cost, which has prompted health economists to ask this question: are these drugs worth the price tag?

Two relatively recent studies have researchers questioning the use of GLP-1 drugs. Even though they have the potential to deliver impressive long-term health improvements, their current high price exceeds the accepted thresholds for cost-effective medications. That not only poses difficult choices for policymakers, but also insurers and patients. 

GLP-1 Drugs: A Pharmaceutical Breakthrough?

Before you start a medication, you should understand how it works. In a nutshell, GLP-1 drugs mimic hormones that regulate hunger and satiety. This process helps people feel full sooner, and they eat less as a result. During clinical trials, GLP-1 drugs have produced weight loss of 15-20%, a percentage range that far exceeds older medications. They don’t just help with weight loss; rather, they may also improve conditions like sleep apnea, chronic kidney disease, and cardiovascular disease. 

That’s a big deal when you consider that obesity increases your risk of developing all of those conditions. According to premature predictions, GLP-1 drugs could potentially prevent thousands of cases of diabetes and cardiovascular disease. That said, there are many natural and healthier ways to contribute to overall health and wellness. The Dherbs Full Body Cleanse is one such program that can help you cleanse the body’s major organs and systems in just 20 days. One of the added benefits is weight loss of 10 to 30 pounds, which is depending on underlying health conditions and body weight. 

Here’s Why The Math Doesn’t Add Up

You can say that GLP-1 drugs offer a range of health benefits, and they do for some people, but at what cost? Generally speaking, a person spends between $700 to $1,000 per month on GLP-1 drugs in the U.S. Accounting for long-term health benefits, researchers have found that these drugs fall short regarding cost effectiveness. 

In an optimistic scenario, researchers used the best weight loss outcomes and long-term risk reductions. Even in that situation, the GLP-1 drugs did not meet the cost effectiveness threshold. This threshold is usually defined as less than $100,000 per quality-adjusted life year (QALY), a standard tool that health economists use to compare medical treatments. One study found that there would have to be a 30% price reduction of tirzepatide to meet the standard mark. For semaglutide drugs, they would need to cost 80% less than what they currently do. 

It’s important to note that Medicare pays for these GLP-1 drugs only if they are prescribed for diabetes or, more recently, sleep apnea. If Medicare expanded coverage, nearly three million beneficiaries would start using drugs over the next decade. Health economists expect those drug costs to total $66 billion, with nearly $18 billion saved through reduced hospitalizations. So over the next 10 years, Medicare would spend $48 billion on these drugs alone. 

Looking For Smarter Solutions

There are many other affordable ways to see better results without having to inject yourself with GLP-1 drugs. Plus, if you want to continue to see results, you have to keep using the medications. It’s much better to develop healthy lifestyle habits and lose weight with a plan in place. Anyone can tell you to exercise regularly, eat better, and establish healthy sleep habits, but those are general recommendations. 

At Dherbs, we pride ourselves in our all-natural products, especially the Full Body Cleanse. This 20-day program has helped people transform their health, and lose between 10 to 30 pounds in the process! Some people cleanse once per year to reset their bodies, while others cleanse back to back until they reach their desired health goals. There are knowledgeable customer service reps and an entire website full of resources to help you succeed. Plus, it’s a fraction of the cost of those GLP-1 drugs! Cleanse today and that weight will melt away, and the results are noticeable within a week, depending on the body and underlying health issues.

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It’s no secret that new weight loss drugs are highly sought after in the United States. The reason for that is because they are highly effective, so long as you continue using them. Ozempic, Wegovy, Zepbound, Mounjaro, and other similar medications work by recreating the effects of GLP-1, a hormone that the gut produces once you finish eating. This hormone reduces both hunger and cravings, helping you to eat less, which promotes weight loss. 

What happens when you stop taking these medications, though? Recent research suggests that you can regain weight once you stop taking them. Health experts have started to refer to this weight gain as “Mounjaro plateau” or “Ozempic rebound.”

Why Do People Stop Using These Medications?

People stop taking these medications for numerous reasons, with a common one being the high cost, which is especially true for people without health insurance. Even if you have health insurance, many providers don’t offer coverage for these drugs. There is a huge demand, supply issues, and many unwanted side effects that come from using these medications. In fact, clinical trials found that up to 10% of users stop using these medications because of side effects, including nausea and disruptive bowel movements. 

It’s possible that the number of people who stop using these medications is higher than that 10% figure. Patients may have less aftercare, support, and accountability than they do in clinical trials. That means there is most likely a higher percentage of people who experience unwanted side effects, which could be easily managed. Doctors also state that people stop using these medications once they meet their goal weight. 

Why Do You Gain Weight Post-Medication?

Ozempic, and other related drugs, were originally intended to help people with type 2 diabetes manage blood sugar levels. During clinical trials, researchers observed weight loss to be a surprising side effect. That got them thinking, so they started to prescribe these medications for weight loss (an off-label purpose). 

In present day, many people with high blood pressure, type 2 diabetes, high cholesterol, or fatty liver disease, have been struggling to lose weight for 20 to 30 years. Drugs like Ozempic or Wegovy help people lose weight by temporarily altering hunger mechanisms. Basically, they provide a synthetic form of GLP-1, which is the hormone that helps you feel satiated and less hungry. At the same time, these drugs also promote an increase in insulin response to food, which works to regulate blood sugar. They also reduce the release of glucagon, a hormone that opposes insulin and tends to increase blood glucose levels. 

When you stop taking these medications, the body naturally produces more ghrelin, the hunger hormone. Once off the medications, the body’s metabolic rate slows down. The combination of a slower metabolic rate and a rapid onset of hunger causes weight gain, especially if there is no modification in lifestyle or diet. 

How Common Is Weight Gain After Stopping Ozempic?

If you use Ozempic to lose weight, the last thing you want is to see the weight return once you stop taking the drug. As it turns out, it is very common for a person to gain weight after quitting Ozempic or similar medication. One study found that people who stopped taking semaglutide (the active ingredient in Ozempic) and quit lifestyle interventions gained two-thirds of their weight back within a year. Another study monitored people who stopped taking tirzepatide, the active ingredient in Zepbound and Mounjaro. Within one year of quitting the drug, they gained more than half the weight they’d lost while on the drug. 

The Takeaway

Before you take any GLP-1 agonist (such as Ozempic), consult your healthcare professional and make sure you understand the risks. Are you using the drug for short-term or long-term results? If you decide to take Ozempic, make sure you understand what will happen once you stop. Your healthcare professional may be able to provide guidance, nutritional advice, and an exercise regimen to help stave off the weight you lost while on the drug.

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GLP-1 medications, such as Ozempic and Wegovy, have been referred to as weight loss “game-changers” or “miracles” for people living with obesity. A 2021 clinical trial found that 86.2% of more than 800 participants experienced significant weight loss after taking 2.4-milligram (mg) doses of semaglutide for 68 weeks. While that sounds promising, 13.8% of participants did not see clinically significant weight loss. 

When it comes to GLP-1 medications, health experts state that people fall into two camps: responder or non-responder. The former indicates that people positively respond to the medications and experience weight loss, while the later indicates that the medications have no effect on the person. Just like with other medications, one prescription is not a one-size-fits-all remedy for every single person. That is especially true for managing obesity. 

Doctors want to remind patients that there tends to be more than one reason why a person ends up in the responder or non-responder categories. Even though the drugs may seem ideal in clinical trials, they do not work for everyone. Just like other medications, they can be unpredictable, both in how they perform and how a person responds to them. Why is that the case? Continue reading to learn about five of the most common reasons, according to health experts. 

Existing Medical Issues

It’s possible for a person to have underlying medical issues that are either untreated, undertreated, or undiagnosed. Hypothyroidism, sleep apnea, and chronic insomnia, for example, can all interfere with weight loss. Those conditions should be dealt with prior to starting a weight loss journey, let alone a weight loss medication. Patients who have an issue with obesity and a binge eating disorder should also address the eating disorder prior to using GLP-1 medications. The binge eating disorder will not correct itself just because you take a GLP-1. 

Medication Interference

People who take GLP-1 drugs alongside other medications may experience less weight loss, or none at all. It’s common for people who take antidepressants and beta blockers to have a difficult time losing weight. Adding a GLP-1 drug to the mix will not encourage weight loss, though. It is better to speak to your healthcare provider about other medications prior to taking a GLP-1. 

Insulin Resistance 

Ozempic is a GLP-1 drug designed to help diabetics lower their A1C. According to a 2022 narrative review, though, people may lose less weight while taking GLP-1 medications. When you have a pre-existing metabolic disease, it can feel like an uphill battle to reverse those abnormalities, especially if you’ve lived with them for a long time. This is due to the physiological response. Typically, GLP-1 aids blood sugar control by stimulating the pancreas to release insulin after meals. That response may be less potent in individuals who do not have type 2 diabetes. The weakened response to GLP-1, then, can make it more difficult to manage blood sugar and lose weight, which can require alternative treatment methods. 

Lifestyle Changes

Trials for semaglutide have included lifestyle intervention for both placebo and medication groups. In a 2021 trial consisting of more than 1,900 adults, for example, researchers wanted to see what influenced the best response to a GLP-1 medication. The general recommendation was that patients should:

• Exercise regularly
• Manage stress
• Maintain a predominantly plant-based diet
• Get quality sleep
• Avoid substance use
• Keep strong social relationships with family and friends

Now, those recommendations are not novel in regards to losing weight and living healthier. In fact, those are things that you should do if you want to be healthier and lose weight. It’s possible that some of these efforts can interfere with GLP-1 medications or reduce their efficacy, but more research is necessary on this matter.

What If You Don’t Experience Weight Loss?

Sometimes, you may not experience weight loss immediately after starting GLP-1 medications. Some people have to take the medication for up to 12 weeks before seeing results. If you have doubts about this, or see that these medications are not moving the needle, consider speaking with your doctor or engage in some of the previously mentioned lifestyle changes. 

You can also consider the Dherbs Full Body Cleanse, which is a 20-day program that has helped millions of people lose weight and experience better overall health. It outlines exactly what you need to do to succeed during the cleanse. Although a lot of people use the cleanse to lose weight (potential to lose 10 to 30 pounds during the 20-day cleanse), its main purpose is to cleanse the body’s major organs and systems. Using the Full Body Cleanse can help the pounds go down and improve overall health and wellness. Not to mention, it’s about one-tenth the cost of GLP-1 medications!

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