We don't recommend taking pain medication because most of them are considered drugs or synthetic. In regards to headaches, they can be a symptom of detoxing. Your body helps to heal itself in addition to the foods we eat. If you're suffering from severe pain while on the cleanse we suggest taking all natural pain relievers or using natural remedies. Aches are usually associated with a magnesium deficiency, increasing the amount of foods rich in magnesium can also be a solution.